BDBM400119 N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((1-(1-methyl-1H-1,2,3-triazol-4-yl)cyclopropyl)amino)-2-oxoacetyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide::US10328053, Compound 98::US10874640, Compound 98::US20230270719, Compound 98

SMILES Cc1c(C(=O)C(=O)NC2(CC2)c2cn(C)nn2)c2CCCn2c1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=DWRBRZDKDOKLTA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400119   

TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400119(N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((1-(1-m...)
Affinity DataEC50:  30.6nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400119(N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((1-(1-m...)
Affinity DataEC50:  30.6nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Gilead Sciences

US Patent
LigandPNGBDBM400119(N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((1-(1-m...)
Affinity DataEC50:  30.6nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent