BDBM400132 N-(3-(difluoromethyl)-4-fluorophenyl)-6-methyl-7-(2-((2-methyl-1-(methylamino)-1-oxopropan-2-yl)amino)-2-oxoacetyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide ::US10328053, Compound 114::US10874640, Compound 114::US20230270719, Compound 114

SMILES CNC(=O)C(C)(C)NC(=O)C(=O)c1c(C)c(C(=O)Nc2ccc(F)c(c2)C(F)F)n2CCCc12

InChI Key InChIKey=ISBDYYOLPRINPR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400132   

TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400132(N-(3-(difluoromethyl)-4-fluorophenyl)-6-methyl-7-(...)
Affinity DataEC50:  156nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM400132(N-(3-(difluoromethyl)-4-fluorophenyl)-6-methyl-7-(...)
Affinity DataEC50:  156nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Gilead Sciences

US Patent
LigandPNGBDBM400132(N-(3-(difluoromethyl)-4-fluorophenyl)-6-methyl-7-(...)
Affinity DataEC50:  156nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent