BDBM401350 US10005762, Example 30

SMILES Cc1cnc(C[C@@](O)([C@@H](N)CC(C)(C)F)C(O)=O)cc1CCCC1CC1

InChI Key InChIKey=VQJHPWGFXARSLD-FXAWDEMLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401350   

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM401350(US10005762, Example 30)
Affinity DataIC50:  3.10nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Astellas Pharma

US Patent
LigandPNGBDBM401350(US10005762, Example 30)
Affinity DataIC50:  1.40nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent