BDBM403443 (6S,9R)- or (6R,9S)- 4-(1-methyl-1H- pyrazol-4-yl)-6,7,8,9- tetrahydro-5H-6,9- epoxycyclo- hepta[b]pyridine-2- carboxamide::US10335399, Example 1-4B::US10806724, Example 1-4B

SMILES Cn1cc(cn1)-c1cc(nc2[C@H]3CC[C@@H](Cc12)O3)C(N)=O

InChI Key InChIKey=SOPCCMQVWBTTME-TVQRCGJNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403443   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403443((6S,9R)- or (6R,9S)- 4-(1-methyl-1H- pyrazol-4-yl)...)
Affinity DataIC50:  1.77E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403443((6S,9R)- or (6R,9S)- 4-(1-methyl-1H- pyrazol-4-yl)...)
Affinity DataIC50:  1.77E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent