BDBM403446 US10335399, Example 1-6A::US10806724, Example 1-6A

SMILES NC(=O)c1cc(c2C[C@H]3CC[C@H](O3)c2n1)-c1ncc(F)cc1F

InChI Key InChIKey=MZCNMHMJEYUDBI-OQPBUACISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403446   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403446(US10335399, Example 1-6A | US10806724, Example 1-6...)
Affinity DataIC50: >3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403446(US10335399, Example 1-6A | US10806724, Example 1-6...)
Affinity DataIC50: >3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent