BDBM403448 US10335399, Example 1-7A::US10806724, Example 1-7A

SMILES NC(=O)c1cc(c2C[C@H]3CC[C@H](O3)c2n1)-c1ncc(Cl)cc1F

InChI Key InChIKey=JWTAIHZJCCKPGE-OQPBUACISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403448   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403448(US10335399, Example 1-7A | US10806724, Example 1-7...)
Affinity DataIC50: >3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403448(US10335399, Example 1-7A | US10806724, Example 1-7...)
Affinity DataIC50: >3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent