BDBM403476 (S)- or (R)-2- ((difluoro- methoxy)methyl)- 5-(1- (difluoromethyl)- 1H-pyrazol-4-yl)- 3,4-dihydro-2H- pyrano[2,3- b]pyridine-7- carboxamide::US10335399, Example 3-4A::US10806724, Example 3-4A

SMILES NC(=O)c1cc(-c2cnn(c2)C(F)F)c2CC[C@H](COC(F)F)Oc2n1

InChI Key InChIKey=STQATWGNSCYSCU-MRVPVSSYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403476   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403476((S)- or (R)-2- ((difluoro- methoxy)methyl)- 5-(1- ...)
Affinity DataIC50:  274nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403476((S)- or (R)-2- ((difluoro- methoxy)methyl)- 5-(1- ...)
Affinity DataIC50:  274nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent