BDBM403477 (R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(1- (difluoromethyl)- 1H-pyrazol-4-yl)- 3,4-dihydro-2H- pyrano[2,3- b]pyridine-7- carboxamide::US10335399, Example 3-4B::US10806724, Example 3-4B

SMILES NC(=O)c1cc(-c2cnn(c2)C(F)F)c2CC[C@@H](COC(F)F)Oc2n1

InChI Key InChIKey=STQATWGNSCYSCU-QMMMGPOBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403477   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403477((R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(1- ...)
Affinity DataIC50:  1.49E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403477((R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(1- ...)
Affinity DataIC50:  1.49E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent