BDBM404098 (2S,5R)-5-isobutyl-1-(2'-methoxy-[1,1'-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid::US10017468, Compound 294::US10781171, Compound 294::US11072582, Compound 294

SMILES COc1ccccc1-c1ccc(cc1)C(=O)N1[C@@H](CC(C)C)CC[C@H]1C(O)=O

InChI Key InChIKey=LCLGFEFYKNOFRA-QUCCMNQESA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 404098   

TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM404098((2S,5R)-5-isobutyl-1-(2'-methoxy-[1,1'-biphenyl]-4...)
Affinity DataEC50:  600nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM404098((2S,5R)-5-isobutyl-1-(2'-methoxy-[1,1'-biphenyl]-4...)
Affinity DataEC50:  600nMAssay Description:The assay was used to determine the activity of the compounds of the invention. The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM404098((2S,5R)-5-isobutyl-1-(2'-methoxy-[1,1'-biphenyl]-4...)
Affinity DataEC50:  600nMAssay Description:The assay was used to determine the activity of the compounds of the invention.The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM404098((2S,5R)-5-isobutyl-1-(2'-methoxy-[1,1'-biphenyl]-4...)
Affinity DataEC50:  600nMAssay Description:The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent