BDBM404173 (2S,5R)-5-(2-chlorophenyl)-1-(3'-cyano-[1,1'-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid::US10017468, Compound 339::US10781171, Compound 339::US11072582, Compound 339
SMILES OC(=O)[C@@H]1CC[C@@H](N1C(=O)c1ccc(cc1)-c1cccc(c1)C#N)c1ccccc1Cl
InChI Key InChIKey=MJGGJISXXONBKK-PKTZIBPZSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 404173
Affinity DataEC50: 600nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:The assay was used to determine the activity of the compounds of the invention. The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM ...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:The assay was used to determine the activity of the compounds of the invention.The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM N...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...More data for this Ligand-Target Pair