BDBM408758 (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(morpholinosulfonyl)-2-nitrophenyl)piperidine-4-carbonyl)pyrrolidine-2-carboxylic acid ::US10358416, Compound 377::US10781171, Compound 377

SMILES OC(=O)[C@@H]1CC[C@@H](N1C(=O)C1CCN(CC1)c1ccc(cc1[N+]([O-])=O)S(=O)(=O)N1CCOCC1)c1ccccc1Cl

InChI Key InChIKey=NLAAXXIDZPFLLF-VWNXMTODSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408758   

TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM408758( (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(morpholinosul...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM408758( (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(morpholinosul...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent