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BDBM408853 US10376531, Compound 3::US10813942, Compound 3

SMILES: CC(=O)N[C@H]1[C@H]2OC[C@](CO)(O2)[C@H](O)[C@@H]1O

InChI Key: InChIKey=HXIYAFJXGOVJDG-OVWPVTOISA-N

Data: 2 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408853   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Asialoglycoprotein receptor 1


(Homo sapiens (Human))
BDBM408853
PNG
(US10376531, Compound 3 | US10813942, Compound 3)
Show SMILES CC(=O)N[C@H]1[C@H]2OC[C@](CO)(O2)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C9H15NO6/c1-4(12)10-5-6(13)7(14)9(2-11)3-15-8(5)16-9/h5-8,11,13-14H,2-3H2,1H3,(H,10,12)/t5-,6-,7-,8?,9+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
PDB
UniChem
PDB
US Patent
n/an/an/a 7.18E+3n/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25 C. Biotinylated ASGPR was immobilized typically at 200...


US Patent US10813942 (2020)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Asialoglycoprotein receptor 1


(Homo sapiens (Human))
BDBM408853
PNG
(US10376531, Compound 3 | US10813942, Compound 3)
Show SMILES CC(=O)N[C@H]1[C@H]2OC[C@](CO)(O2)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C9H15NO6/c1-4(12)10-5-6(13)7(14)9(2-11)3-15-8(5)16-9/h5-8,11,13-14H,2-3H2,1H3,(H,10,12)/t5-,6-,7-,8?,9+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
PDB
UniChem
PDB
US Patent
n/an/an/a 7.18E+3n/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25 C. Biotinylated ASGPR was immobilized typically at 200...


US Patent US10376531 (2019)


BindingDB Entry DOI: 10.7270/Q2542QZJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)