BDBM412293 US10399945, Example 32::US10927079, Compound 32

SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccc(Br)cc23)c1)-c1ccccc1

InChI Key InChIKey=AICYKKCIWBCNKL-FYYLOGMGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412293   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412293(US10399945, Example 32 | US10927079, Compound 32)
Affinity DataIC50: <0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412293(US10399945, Example 32 | US10927079, Compound 32)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent