BDBM412299 US10399945, Example 36::US10669239, Compound 36::US10927079, Compound 36

SMILES CC1(C)C[C@@H](O)[C@H](NC(=O)Nc2cccnc2-c2ccccc2)c2cc(F)c(F)cc12

InChI Key InChIKey=IMFBAKHOZNLTRT-IFMALSPDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412299   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412299(US10399945, Example 36 | US10669239, Compound 36 |...)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412299(US10399945, Example 36 | US10669239, Compound 36 |...)
Affinity DataIC50: <0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412299(US10399945, Example 36 | US10669239, Compound 36 |...)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent