BDBM413387 US10407422, Example 130

SMILES Nc1cc(Cc2cnn(Cc3ccc4CNCCc4c3)c2)c2nn[nH]c2n1

InChI Key InChIKey=QALYNGDUFROUBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413387   

TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM413387(US10407422, Example 130)
Affinity DataIC50:  8nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent