BDBM416419 US10301261, Compound IN-5::US10829448, Compound IN-5

SMILES CCn1c(Cc2ccc3OC(F)(F)Oc3c2)cc2cc(ccc12)C(=O)N[C@@H](CO)c1ccc(cn1)S(=O)(=O)CC

InChI Key InChIKey=PQCLNDQHALTDBL-QHCPKHFHSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 416419   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM416419(US10301261, Compound IN-5 | US10829448, Compound I...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM416419(US10301261, Compound IN-5 | US10829448, Compound I...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM416419(US10301261, Compound IN-5 | US10829448, Compound I...)
Affinity DataIC50: <100nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted NanolucŪ luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent