BDBM416456 (R)-N-(2-amino-1-(4-(ethylsulfonyl)phenyl)ethyl)-1-ethyl-2-(4-(trifluoromethyl)phenoxy)-1H-benzo[d]imidazole-5-carboxamide::US10301261, Compound BE-11::US10829448, Compound BE-11
SMILES CCn1c(Oc2ccc(cc2)C(F)(F)F)nc2cc(ccc12)C(=O)N[C@@H](CN)c1ccc(cc1)S(=O)(=O)CC
InChI Key InChIKey=BUPKBOVVJIVCDT-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 416456
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted NanolucŪ luci...More data for this Ligand-Target Pair