BDBM425462 4-[6-(3,5-dimethylisoxazol-4-yl)-1-[1- (2-pyridyl)ethyl]pyrrolo[3,2-b]pyridin- 3-yl]benzoic acid::US10519177, Compound P-0369

SMILES CC(c1ccccn1)n1cc(-c2ccc(cc2)C(O)=O)c2ncc(cc12)-c1c(C)noc1C

InChI Key InChIKey=AMSUHYUVOVCWTP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425462   

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425462(4-[6-(3,5-dimethylisoxazol-4-yl)-1-[1- (2-pyridyl)...)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425462(4-[6-(3,5-dimethylisoxazol-4-yl)-1-[1- (2-pyridyl)...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair