BDBM4300 (2E)-3-(3,4-dihydroxyphenyl)-2-[(2,4,6-trimethylphenyl)carbonyl]prop-2-enenitrile::Tyrphostin deriv. 39
SMILES Cc1cc(C)c(C(=O)C(=Cc2ccc(O)c(O)c2)C#N)c(C)c1
InChI Key InChIKey=CVJUVNFCJFFASS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 4300
Affinity DataIC50: 1.07E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Tennessee Health Sciences Center
Curated by ChEMBL
University Of Tennessee Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair