BDBM433319 3-(ethylthio)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5,7,7-trimethyl-7,8-dihydro-2H-imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(5H)-one::US10561656, Example 2

SMILES CCSc1c2c(nn1Cc1ccc(cc1)-c1cccc(F)n1)N1CC(C)(C)N=C1N(C)C2=O

InChI Key InChIKey=WSKXIQFITDCMOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 433319   

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Intra-Cellular Therapies

US Patent
LigandPNGBDBM433319(3-(ethylthio)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5...)
Affinity DataIC50:  4.00E+3nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies

US Patent
LigandPNGBDBM433319(3-(ethylthio)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5...)
Affinity DataIC50:  1nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent