BDBM43562 2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl-1,3,4-thiadiazole::2-[(1-phenyl-1,2,3,4-tetrazol-5-yl)sulfanyl]-5-propylsulfanyl-1,3,4-thiadiazole::2-[(1-phenyl-5-tetrazolyl)thio]-5-(propylthio)-1,3,4-thiadiazole::2-[(1-phenyltetrazol-5-yl)thio]-5-(propylthio)-1,3,4-thiadiazole::MLS000056566::SMR000064678::cid_2536033

SMILES CCCSc1nnc(Sc2nnnn2-c2ccccc2)s1

InChI Key InChIKey=WHUUOISPINJTGK-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43562   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43562(2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl...)
Affinity DataIC50: >6.19E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43562(2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl...)
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43562(2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl...)
Affinity DataEC50:  1.45E+4nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43562(2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl...)
Affinity DataEC50:  2.20E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43562(2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl...)
Affinity DataEC50:  1.17E+5nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay