BDBM437687 US10617706, Example 121

SMILES CC1(C)OB(OC1(C)C)c1cccc(COc2ccc(cc2)N2C3NC(=O)NC(=O)C3=Cc3ccc(cc23)C#N)c1

InChI Key InChIKey=QTNLBYOAYNHEFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437687   

TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437687(US10617706, Example 121)
Affinity DataIC50:  47nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent