BDBM438762 4-(2-(2-((2,2'-dichloro-3'-(5- isopropyl-1-methyl-4,5,6,7- tetrahydro-1H-imidazo[4,5- c]pyridine-2-carboxamido)- [1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)ethyl)bicyclo[2.2.1]heptane- 1-carboxylic acid::US10618916, Example 5::US10906920, Example 5::US11414433, Example 5

SMILES CC(C)N1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

InChI Key InChIKey=ZMFDIJDQQHZVIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438762   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM438762(4-(2-(2-((2,2'-dichloro-3'-(5- isopropyl-1-methyl-...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Incyte

US Patent
LigandPNGBDBM438762(4-(2-(2-((2,2'-dichloro-3'-(5- isopropyl-1-methyl-...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM438762(4-(2-(2-((2,2'-dichloro-3'-(5- isopropyl-1-methyl-...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent