BDBM438786 5-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-1-yl)ethyl)-1-methyl- 4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)-2,2'-dichloro- [1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)methyl)-1H-pyrazole-3- carboxylic acid::US10618916, Example 26::US10906920, Example 26::US11414433, Example 26

SMILES Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(Cc4cc(n[nH]4)C(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=LOTFRULREAEQNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438786   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM438786(5-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Incyte

US Patent
LigandPNGBDBM438786(5-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM438786(5-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent