BDBM438820 4-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-1-yl)ethyl)-1-methyl- 4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)-2,2'- dimethyl-[1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)methyl)bicyclo[2.2.1] heptane-1-carboxylic acid::US10618916, Example 55::US10906920, Example 55::US11414433, Example 55
SMILES Cc1c(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)cccc1-c1cccc(NC(=O)c2nc3CN(CC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1C
InChI Key InChIKey=CGIRJQFTRQNFJD-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 438820
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair