BDBM441836 US10647665, Example 1-22b::US10851050, Example I-22b

SMILES Cn1cc(cn1)-c1cccc(OC(F)(F)F)c1-c1ccc(NC(=O)NCc2ccc(CC(O)=O)cc2)cc1

InChI Key InChIKey=MSNGRTAWPJEDPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 441836   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

US Patent
LigandPNGBDBM441836(US10647665, Example 1-22b | US10851050, Example I-...)
Affinity DataIC50:  2.75E+3nMAssay Description:The inhibitory activity of compounds on RORγ receptor was determined by fluorescence resonance energy transfer (FRET) experiments. The inhibitor...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

US Patent
LigandPNGBDBM441836(US10647665, Example 1-22b | US10851050, Example I-...)
Affinity DataIC50:  2.75E+3nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent