BDBM442768 1,6-Dimethyl-N- {1-[4-(trifluoro- methyl)phenyl]- cyclobutyl}-1H- pyrazolo[3,4-d]- pyrimidin-4-amine::US10647727, Example 25
SMILES Cc1nc(NC2(CCC2)c2ccc(cc2)C(F)(F)F)c2cnn(C)c2n1
InChI Key InChIKey=ZLGZMDIZQFJTID-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 442768
Affinity DataKi: 358nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 430nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair