BDBM442774 N-(1-(3-Fluoro-4-(trifluoromethyl)phenyl)cyclopropyl)-7-methylimidazo[1,2-a]pyrimidin-5-amine::US10647727, Example 31

SMILES Cc1cc(OC2(CC2)c2ccc(c(F)c2)C(F)(F)F)n2ccnc2n1

InChI Key InChIKey=LYXOWFCHMGUTIW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442774   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442774(N-(1-(3-Fluoro-4-(trifluoromethyl)phenyl)cycloprop...)
Affinity DataKi:  55nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent