BDBM444452 US10662159, Example 40
SMILES OC[C@@H](OC(=O)N1CCc2c(Br)cccc2C1)C(F)(F)F
InChI Key InChIKey=NRFAEYWXDBVJGR-LLVKDONJSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 444452
Affinity DataIC50: 55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair