BDBM444739 (R)-1-(3-(3-(4-(4-methylpiperazin-1- yl)phenyl)-1H-pyrazolo [4,3-c]pyridin-1-yl)pipcridin-1-yl)prop-2- en-1-one::US10662187, Compound 109::US10793566, Compound 109

SMILES CN1CCN(CC1)c1ccc(cc1)-c1nn(C2CCCN(C2)C(=O)C=C)c2ccncc12

InChI Key InChIKey=IPMIOGFXPAZPLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444739   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444739((R)-1-(3-(3-(4-(4-methylpiperazin-1- yl)phenyl)-1H...)
Affinity DataIC50:  550nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444739((R)-1-(3-(3-(4-(4-methylpiperazin-1- yl)phenyl)-1H...)
Affinity DataIC50:  550nMAssay Description:Measurements were performed in a reaction volume of 15 μL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 μM peptide subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent