BDBM44504 2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-pyridylidene)methyl]-2-furyl]benzoic acid ethyl ester::2-chloro-5-[5-[(E)-(5-cyano-4-methyl-2,6-dioxo-3-pyridinylidene)methyl]-2-furanyl]benzoic acid ethyl ester::MLS000519146::SMR000129565::cid_6522725::ethyl 2-chloranyl-5-[5-[(E)-[5-cyano-4-methyl-2,6-bis(oxidanylidene)pyridin-3-ylidene]methyl]furan-2-yl]benzoate::ethyl 2-chloro-5-[5-[(E)-(5-cyano-4-methyl-2,6-dioxopyridin-3-ylidene)methyl]furan-2-yl]benzoate

SMILES CCOC(=O)c1cc(ccc1Cl)-c1ccc(\C=C2\C(=O)NC(=O)C(C#N)=C2C)o1

InChI Key InChIKey=WJDZZRSELRBXOP-NTEUORMPSA-N

Data  6 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 44504   

TargetEphrin type-A receptor 4(Mus musculus)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataIC50:  2.53E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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TargetEphrin type-A receptor 4(Mus musculus)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
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TargetEukaryotic translation initiation factor 4 gamma 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataIC50:  2.34E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
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TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataIC50:  752nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
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TargetVacuolar aminopeptidase 1(Saccharomyces cerevisiae)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataEC50:  1.36E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
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TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataEC50:  1.99E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
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TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataEC50:  1.74E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
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TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataIC50:  8.01E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
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Target60S ribosomal protein L19-A(Saccharomyces cerevisiae)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataEC50:  3.35E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM44504(2-chloro-5-[5-[(E)-(5-cyano-2,6-diketo-4-methyl-3-...)
Affinity DataIC50:  4.13E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay