BDBM445331 US10669239, Compound 56::US10927079, Compound 56

SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccnc(CO)c1)-c1ccccc1

InChI Key InChIKey=PMRXIUUXGGEYOQ-GGXMVOPNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445331   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM445331(US10669239, Compound 56 | US10927079, Compound 56)
Affinity DataIC50: <0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM445331(US10669239, Compound 56 | US10927079, Compound 56)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent