BDBM448466 US10695347, Compound I-98

SMILES COc1cc(N2CCC(CC2)N(C)C)c(C)cc1Nc1ncc(Cl)c(Nc2cccnc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=SKIHVNFIZKUPKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448466   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute

US Patent
LigandPNGBDBM448466(US10695347, Compound I-98)
Affinity DataIC50: <1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute

US Patent
LigandPNGBDBM448466(US10695347, Compound I-98)
Affinity DataIC50: <1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent