BDBM458385 1-[3-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiazol-5-yl)methyl]-5-methyl-pyrrolidin-3-yl]oxy-5,7-dihydropyrrolo[3,4-b]pyridin-6-yl]ethanone::US10752632, Example 4::US10836773, Example 4
SMILES C[C@H]1C[C@H](CN1Cc1cc2nc(C)sc2cc1F)Oc1cnc2CN(Cc2c1)C(C)=O
InChI Key InChIKey=HDEZEDNSDNXGSS-ORAYPTAESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 458385
Affinity DataIC50: 0.592nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.592nMAssay Description:Inhibition of full-length human N-terminal poly-His tagged OGA expressed in baculovirus infected Sf9 cells using FD-GlcNAc as substrate preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.592nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair