BDBM458758 (R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-2-yl)-1H-pyrazole-4-carboxamide::US10758530, Compound 15

SMILES C[C@@H]1CNC(=O)c2cc3ccc(NC(=O)c4cnn(Cc5ccccc5)c4)nc3n12

InChI Key InChIKey=XYMNFMNOEWBPNB-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 458758   

TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM458758((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...)
Affinity DataIC50:  94nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM458758((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...)
Affinity DataIC50:  8nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM458758((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...)
Affinity DataIC50:  6nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM458758((R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydrop...)
Affinity DataIC50:  23.6nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent