BDBM46100 6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carboxamide::6-hydroxy-2,4-dioxo-N-phenyl-1H-pyrimidine-5-carboxamide::6-oxidanyl-2,4-bis(oxidanylidene)-N-phenyl-1H-pyrimidine-5-carboxamide::UPDDI-00294852::US9428466, 2-oxo-desthiomerbarone::cid_100782

SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccccc1

InChI Key InChIKey=VKWYRWQIBQMDFJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 46100   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM46100(6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carb...)
Affinity DataIC50: >5.00E+4nMAssay Description:List of compounds to be tested: 33 component starting materials and chemical analogs of the hits identified in the in vitro PLK1-PBD binding primary ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM46100(6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carb...)
Affinity DataIC50: >3.00E+5nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM46100(6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carb...)
Affinity DataIC50:  1.20E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In DepthDetails US Patent