BDBM463149 4-Amino-2-{8-[(2-fluorophenyl)methyl]imidazo[1,2-a]pyrazin-6-yl}-5-[3-hydroxy-4-(trifluoromethyl)phenyl]-5-methyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one::US10780092, Example 3-B

SMILES CC1(C(=O)Nc2nc(nc(N)c12)-c1cn2ccnc2c(Cc2ccccc2F)n1)c1ccc(c(O)c1)C(F)(F)F

InChI Key InChIKey=MWQKDJBPUXNXJC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463149   

TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM463149(4-Amino-2-{8-[(2-fluorophenyl)methyl]imidazo[1,2-a...)
Affinity DataKi:  0.219nMAssay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent