BDBM463256 4-Amino-2-(8-(cyclo- hexylmethyl)-[1,2,4]- triazolo[1,5-a]pyrazin- 6-yl)-5-(4-hydroxy- pyridin-2-yl)-5-methyl- 5,7-dihydro-6H-pyrrolo- [2,3-d]pyrimidin-6-one::US10780092, Example 109-A

SMILES CC1(C(=O)Nc2nc(nc(N)c12)-c1cn2ncnc2c(CC2CCCCC2)n1)c1cc(O)ccn1

InChI Key InChIKey=YFJFTQZJSYTWAH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463256   

TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM463256(4-Amino-2-(8-(cyclo- hexylmethyl)-[1,2,4]- triazol...)
Affinity DataKi:  0.634nMAssay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent