BDBM463346 3-amino-N-[2-(5-chloro-2-methylphenoxy)ethyl]-1-({4-[(2-oxopyridin-1-::US10781181, Example 14
SMILES Cc1ccc(Cl)cc1OCCNC(=O)c1cn(Cc2ccc(Cn3ccccc3=O)cc2)nc1N
InChI Key InChIKey=HIPKPQWZXBVAPK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 463346
Affinity DataIC50: >4.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods. Human KLK1 (Callbiochem) was incubated at 25° C. with the fluoroge...More data for this Ligand-Target Pair
Affinity DataIC50: 161nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods. Human plasma kallikrein (Protogen) was incubated at 2...More data for this Ligand-Target Pair