BDBM463497 3-(3,3-Dimethylpiperidin-1-yl)-2-(4-fluorophenyl)quinoxaline-6-carboxylic acid::US10781185, Example 79::US11459307, Example 79

SMILES CC1(C)CCCN(C1)c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(O)=O

InChI Key InChIKey=WFZHQPVGJAHSMC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 463497   

TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM463497(3-(3,3-Dimethylpiperidin-1-yl)-2-(4-fluorophenyl)q...)
Affinity DataIC50: <1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM463497(3-(3,3-Dimethylpiperidin-1-yl)-2-(4-fluorophenyl)q...)
Affinity DataIC50: <1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase [879-1323](Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM463497(3-(3,3-Dimethylpiperidin-1-yl)-2-(4-fluorophenyl)q...)
Affinity DataIC50: <1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase(Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM463497(3-(3,3-Dimethylpiperidin-1-yl)-2-(4-fluorophenyl)q...)
Affinity DataIC50: <1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent