BDBM463563 (2S)-3-[(3S,4)S- 3-[(1R)-1- hydroxyethyl]-4- {4-methoxy-3- [(1-(6- chloropyrimidin- 4-yl)azetidin-3- yl)oxy]phenyl}- 3- methylpyrrolidin- 1-yl]-3- oxopropane-1,2-::US10781202, Example 8

SMILES COc1ccc(cc1OC1CN(C1)c1cc(Cl)ncn1)[C@@H]1CN(C[C@@]1(C)[C@@H](C)O)C(=O)[C@@H](O)CO

InChI Key InChIKey=LUVVJNFXZRUYEN-RHFMDAINSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463563   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM463563((2S)-3-[(3S,4)S- 3-[(1R)-1- hydroxyethyl]-4- {4-me...)
Affinity DataIC50:  0.530nMAssay Description: PDE4A, PDE4B, PDE4C, PDE4D, and PDE5 human recombinant proteins are expressed and purified from Saccharomyes cerevisiae that lack endogenous PDEs. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent