BDBM463760 2-[1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-4-(trifluoromethyl)-2-pyridyl]azetidin-3-yl]acetic Acid::US10781212, Example 2

SMILES C[C@H]1CCN1c1nc(cc(c1C#N)C(F)(F)F)N1CC(CC(O)=O)C1

InChI Key InChIKey=SQRDQWXYQOPZMI-VIFPVBQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 463760   

TargetIsoform A of Ketohexokinase (Peripheral)(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM463760(2-[1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-4-(tr...)
Affinity DataIC50:  37nMAssay Description:The intrinsic potency of the compounds may be measured using an enzymatic assay which measures the production of F P. Compounds are prepared in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM463760(2-[1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-4-(tr...)
Affinity DataIC50:  27nMAssay Description:The intrinsic potency of the compounds may be measured using an enzymatic assay which measures the production of F P. Compounds are prepared in DMSO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent