BDBM46377 4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazonoyl)-2-methoxyphenyl methyl carbonate::MLS000545073::SMR000161216::[4-[[2-[(2-bromophenyl)methylsulfanyl]ethanoylhydrazinylidene]methyl]-2-methoxy-phenyl] methyl carbonate::[4-[[[2-[(2-bromophenyl)methylsulfanyl]acetyl]hydrazinylidene]methyl]-2-methoxyphenyl] methyl carbonate::carbonic acid [4-[[[2-[(2-bromobenzyl)thio]acetyl]hydrazono]methyl]-2-methoxy-phenyl] methyl ester::carbonic acid [4-[[[2-[(2-bromophenyl)methylthio]-1-oxoethyl]hydrazinylidene]methyl]-2-methoxyphenyl] methyl ester::cid_987778

SMILES COC(=O)Oc1ccc(C=NNC(=O)CSCc2ccccc2Br)cc1OC

InChI Key InChIKey=PPGGAPXEUXGXFM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 46377   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM46377(4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazo...)
Affinity DataIC50:  2.07E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM46377(4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazo...)
Affinity DataIC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM46377(4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazo...)
Affinity DataIC50:  3.89E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetX-box-binding protein 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM46377(4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazo...)
Affinity DataIC50:  1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM46377(4-(2-{[(2-bromobenzyl)sulfanyl]acetyl}carbohydrazo...)
Affinity DataIC50:  3.89E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay