BDBM463843 2,2,4-trimethyl-8-(6-methyl-7- oxo-6,7-dihydro-1H- pyrrolo[2,3-c]pyridin-4-yl)-6- (piperidin-1-ylsulfonyl)-2H- 1,4-benzoxazin-3(4H)-one::US10781209, Example 73

SMILES CC(C)C1Oc2c(cc(c(C)c2N(C)C1=O)S(=O)(=O)N1CCCCC1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 463843   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM463843(2,2,4-trimethyl-8-(6-methyl-7- oxo-6,7-dihydro-1H-...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM463843(2,2,4-trimethyl-8-(6-methyl-7- oxo-6,7-dihydro-1H-...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent