BDBM464088 US10787436, Compound I-24

SMILES Cc1ccc(NC(=O)c2ccc(NC(=O)C=C)cc2)cc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=OHOSYPVIDYXWQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 464088   

TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM464088(US10787436, Compound I-24)
Affinity DataIC50: <100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM464088(US10787436, Compound I-24)
Affinity DataIC50:  40nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent