BDBM464206 8-acetyl-1-(3-fluoro-2-methylbenzyl)-3- (6-methoxy-5-(1H-pyrazol-4-yl)pyridin- 2-yl)-1,3,8-triazaspiro[4.5]decan-2-one::US10787450, Example 86
SMILES COc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CC2)C(C)=O)N(Cc2cccc(F)c2C)C1=O
InChI Key InChIKey=ZJYXTUZFBGINJL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464206
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair