BDBM464263 3-(4-(1H-pyrazol-4- yl)phenyl)-1-(3- fluoro-5- methoxybenzyl)-8-(2- hydroxyethyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 144
SMILES COc1cc(F)cc(CN2C(=O)N(CC22CCN(CCO)CC2)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key InChIKey=BZVWVGSIDJNJMQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464263
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair