BDBM464272 3-(6-ethyl-5-(1H- pyrazol-4-yl)pyridin- 2-yl)-1-(3-fluoro-5- methoxybenzyl)-8-(2- hydroxyethyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 153
SMILES CCc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CCO)CC2)N(Cc2cc(F)cc(OC)c2)C1=O
InChI Key InChIKey=APFLJJGINAJJFT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464272
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair