BDBM464275 3-(6-ethyl-5-(1H- pyrazol-4-yl)pyridin- 2-yl)-1-(3-fluoro-2- methylbenzyl)-8-(2- hydroxypropyl)-1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 156
SMILES CCc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CC(C)O)CC2)N(Cc2cccc(F)c2C)C1=O
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464275
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair