BDBM464320 8-(3,3- difluorocyclobutane- carbonyl)-3-(6-ethyl-5- (1H-pyrazol-4- yl)pyridin-2-yl)-1-(3- methoxybenzyl)- 1,3,8- triazaspiro[4.5]decan- 2-one::US10787450, Example 202
SMILES CCc1nc(ccc1-c1cn[nH]c1)N1CC2(CCN(CC2)C(=O)C2CC(F)(F)C2)N(Cc2cccc(OC)c2)C1=O
InChI Key InChIKey=COBLGTTVCMEWFD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 464320
Affinity DataIC50: <3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair